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Whilst small-rely MBL almost never progresses to CLL, superior-depend MBL progresses to CLL requiring therapy in a charge of 1% to two% annually. Large-count MBL is distinguished from Rai 0 CLL determined by whether the B-mobile count is higher than or underneath 5 × 109/L. Even though people with both significant-depend MBL and CLL Rai stage 0 ar